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A sparsely decorated Chicago eatery with a focus on farm-fresh ingredients and flavors from the Midwest has been dubbed the best restaurant in North America. One of several regional efforts curated by the “World’s 50 Best” brand by culinary media company William Reed, the second-ever North America’s 50 Best Restaurants list is led by Smyth, located in Chicago’s epicurean-centric West Loop neighborhood and the only reastaurant in the city that currently holds three Michelin stars.

Smyth was founded by culinary power couple John and Karen Uri Shields, who originally met while working in the kitchen at the now-defunct Charlie Trotter’s, a trailblazing venue in Chicago’s fine dining scene. The pair later moved to rural Smyth County, Virginia where they honed the use of locally grown and foraged produce at their Town House restaurant, before they returned in 2016 to open Smyth.

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Following Smyth in the top 10 is Eight (No.2) in Calgary, named The Best Restaurant in West Canada 2026, and Restaurant Pearl Morissette (No.3) in Lincoln, awarded The Best Restaurant in Central Canada 2026. Dakar NOLA (No.4) in New Orleans is awarded The Best Restaurant in South USA 2026, Mon Lapin (No.5) from Montreal is The Best Restaurant in East Canada 2026, and Albi (No.6) from Washington DC, is also recognized as The Best Restaurant in Northeast USA 2026. Atomix (No.7) in New York City, Quetzal (No.8) in Toronto, Tanière3 (No.9) in Quebec City, and César (No.10) in New York City complete the top 10. Overall, the list includes 14 restaurants from Canada and 36 from the United States.

Faye Huggett, Director of Community for North America’s 50 Best Restaurants, says: “The second edition of North America’s 50 Best Restaurants celebrates the extraordinary diversity, creativity, and excellence that define the region’s dining scene. From pioneering dining institutions to bold new voices, the list reflects the depth and dynamism of North America’s rich culinary landscape. Congratulations to Smyth, crowned The Best Restaurant in North America 2026, and to all the chefs and teams whose passion and creativity continue to push the industry forward.” See the full list of the North America’s 50 Best Restaurants below.

North America’s 50 Best Restaurants 2026

1. Smyth – Chicago (The Best Restaurant in North America; The Best Restaurant in Midwest USA)
2. Eight – Calgary (The Best Restaurant in West Canada; Highest New Entry Award)
3. Restaurant Pearl Morissette – Lincoln (The Best Restaurant in Central Canada; Art of Hospitality Award)
4. Dakar NOLA – New Orleans (The Best Restaurant in South USA)
5. Mon Lapin – Montreal (The Best Restaurant in East Canada)
6. Albi – Washington DC (The Best Restaurant in Northeast USA; Highest Climber Award)
7. Atomix – New York
8. Quetzal – Toronto
9. Tanière3 – Quebec City
10. César – New York
11. Kalaya – Philadelphia
12. Le Veau d’Or – New York
13. Le Bernardin – New York
14. Kabawa – New York (New Entry)
15. Le Violon – Montreal
16. SingleThread – Healdsburg (The Best Restaurant in West USA)
17. Published on Main – Vancouver
18. Jungsik – New York
19. Penny – New York
20. Emeril’s – New Orleans
21. Chubby Fish – Charleston
22. Saison – San Francisco
23. Aska – New York
24. Moon Rabbit – Washington DC
25. Edulis – Toronto (New Entry)
26. Holbox – Los Angeles
27. Beba – Montreal
28. Mhel – Toronto
29. Avize – Atlanta (New Entry)
30. Acamaya – New Orleans (New Entry)
31. Addison by William Bradley – San Diego (New Entry)
32. Providence – Los Angeles
33. Benu – San Francisco
34. Sabayon – Montreal (New Entry)
35. AnnaLena – Vancouver (New Entry)
36. Corima – New York
37. Dōgon by Kwame Onwuachi – Washington DC
38. Torrisi – New York (New Entry)
39. Tatiana by Kwame Onwuachi – New York (New Entry)
40. Friday Saturday Sunday – Philadelphia
41. Semma – New York (New Entry)
42. Pascual – Washington DC (New Entry)
43. Gramercy Tavern – New York (New Entry)
44. Atelier Crenn – San Francisco (Sustainable Restaurant Award)
45. Sons & Daughters – San Francisco (New Entry)
46. Somni – Los Angeles (New Entry)
47. Wild Blue – Whistler (New Entry)
48. The Pine – Collingwood (New Entry)
49. Kato – Los Angeles
50. Diane’s Place – Minneapolis (New Entry)

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Amid the rise of certain GLP-1 agonist medications, many have taken an interest in the wider world of GLP-1 peptides. These supplements are generally aimed at fat loss and metabolic optimization, though taking advantage of their unique benefits isn’t always straightforward. When exploring this environment, it is important to adopt a science-backed, responsible approach in order to avoid health risks. 

Navigating A Gray Space 

GLP-1 supplements exist in a variety of forms; therefore, each has a range of efficacy, cost, and safety. The United States Food and Drug Administration (FDA) approved the first GLP-1 supplement in 2005, and there are currently seven such GLP-1 agonist medications available in the market today. Ultimately, researchers are still learning about where these supplements might benefit users. 

That said, many GLP-1 supplements exist outside of direct regulation, which can make it difficult for consumers to make decisions. This is especially true when one can’t afford regulated products or tolerate their side effects, which might lead to exploring alternatives. It is possible for other GLP-1 supplements to have a positive impact, but blindly engaging with this space introduces uncertainty. 

“The bottom line,” a Harvard professor said, “is companies selling GLP-1 supplements don’t have to test their products in clinical trials or prove that they increase hormone production, reduce cravings, control appetite, or quiet food noise. They are not required to provide any evidence before they go to a market.” 

Searching For Trusted Advice 

In a space where uncertainty is a prevalent concern, advice from those experienced in GLP-1 and other supplements may be valuable. Where many rely on trend-chasing or secondhand knowledge, some participants in the market boast decades of experience. Others have gone on transformative journeys of their own, establishing themselves as authorities in an otherwise complex environment. 

Metabolic Awakening with GLP-1 Peptides was written as a guidebook for many readers, reflecting the lived experience of Jay Campbell, a renowned voice in health optimization, hormonal science, and human longevity. Within the book, Campbell offers insight based on more than 25 years of successful supplement use aimed at long-term health. From this, he takes an esoteric subject matter and distills it into understandable data for the reader. 

“Through his books, podcast, and coaching,” a representative said, “[Campbell] empowers people to break free from the broken ‘sick-care’ system, avoid misinformation; [and] live stronger, leaner, and more purposeful lives.” 

Maintaining Responsible Awareness 

Ultimately, whatever advice one turns to should be rooted in a science-backed understanding. Without this measure of responsibility, it is possible to gather information from unreliable sources. Poorly-managed supplement use can introduce real danger, despite what one might have been told by other sources. One’s commitment should be to cutting away the noise, rather than introducing more. 

GLP-1 peptide supplements, although largely regulated solutions, can make an impact on one’s metabolism. Finding the right solution is a matter of working with trusted individuals whose support is based on real scientific understanding. Without such guidance, one may introduce risk to supplements that should be beneficial. With it, finding clarity in this environment is possible. 

“Most people don’t get into trouble because peptides don’t work. They get into trouble because they don’t understand how to use them,” said Campbell. “In a space like this, education isn’t optional, it’s the difference between progress and risk.” 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. This article is for informational purposes only and does not substitute for professional medical advice. If you are seeking medical advice, diagnosis or treatment, please consult a medical professional or healthcare provider. 

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