Get Super Smash Bros. Ultimate for $39.99, Super Mario Odyssey for $34.99 and more, plus Labo deals and savings on the Switch itself.
Another killer TV deal: The 49-inch TCL Roku for $200 – CNET
It’s a 3-Series model, but still perfectly good and an amazing buy — less than a week before the Super Bowl.
Record Number Now Consider Climate Change Personal Issue, Poll Finds

According to a Yale and George Mason poll, more than 70 percent of Americans now feel climate change is personally important to them, a 9 percent increase from last March and a record in polling that reveals rapidly changing perspectives nationwide. What do you think?
Finding second hits to knock out leukemia
Targeted drugs are a cornerstone of personalized medicine, yet come with important drawbacks. They restrain disease progression — but rarely eradicate the cancer. Patients therefore need to take the drugs essentially forever, exposing them to severe side effects and incurring high costs for the healthcare system. Combination therapies could potentially overcome these limitations. A new study shows how epigenetic analysis and automated microscopy help prioritize new drug combinations for leukemia therapy.
How gender disparities in salary add up over a lifetime
Around the country, women physician researchers make 7 to 8 percent less per year than men. Women faculty are likely to accumulate much less wealth over their lifetimes, researchers found.
Cancer: A mutation that breaks gene interplay in 3D
Scientists have discovered how a mutated gene can affect the three-dimensional interactions of genes in the cell, leading to various forms of cancer.
Converting Wi-Fi signals to electricity with new 2D materials
Imagine a world where smartphones, laptops, wearables, and other electronics are powered without batteries. Researchers have taken a step in that direction, with the first fully flexible device that can convert energy from Wi-Fi signals into electricity that could power electronics.
What you eat could impact your brain and memory
High levels of a satiety hormone could decrease a person’s likelihood of developing Alzheimer’s disease. For individuals who have higher levels of the hormone, their chance of having mild cognitive impairment or Alzheimer’s disease decreased by 65 percent.
Grandma’s #MeToo Stories Fucking Horrifying

TULSA, OK—Visibly upset by the lengthy conversation with her paternal grandmother, bistro manager Allison Boyer, 24, admitted Monday that her grandmother’s #MeToo stories of daily life as a single woman in the 1950s and ’60s were “fucking horrifying.” “All I did was ask her about what her life was like before she met…
Nissan Leaf E+ may lose 25 miles of range in higher trims, report says – Roadshow
The EPA hasn’t announced official figures yet, but the report cites official documents from CARB.